The 4th Annual Duke Center for Brain and Spine Metastasis (DCBSM) Research Retreat is a multidisciplinary educational program designed to bring together physicians, researchers, advanced practice providers, nurses, trainees, and other healthcare professionals involved in the care and study of patients with brain and spine metastases. The retreat features presentations from leading experts, scientific research updates, and interactive discussions focused on emerging advances in the diagnosis, treatment, translational research, and multidisciplinary management of metastatic disease to the central nervous system. The program fosters collaboration across specialties, promotes the exchange of scientific knowledge, and supports the translation of research findings into improved patient care.