Journal Review in Transplant Surgery: Use of Normothermic Machine Perfusion (NMP) in Liver Transplant

Surgical resection of perihilar cholangiocarcinoma (pCCA) is one of the highest-risk elective operations performed. The obstructive jaundice suffered by patients preoperatively, central location of the tumors, and extensive nature of the resection make pCCA one of the most challenging HPB disease processes. In this episode from the HPB team at Behind the Knife, listen in on the discussion about perioperative strategies to improve outcomes for surgical resection of perihilar cholangiocarcinoma.

Target Audience

  • Nurses
  • Nurse Practitioners
  • Physicians
  • Physician Assistants

Learning Objectives

  • Describing the principles of normothermic machine perfusion (NMP) and how it differs from static cold storage.
  • Summarizing the design and key outcomes of the PROTECT trial and the Chapman et al. trial on NMP in liver transplantation.
  • Recognizing the clinical scenarios where NMP provides the greatest benefit, particularly in high-risk grafts (e.g., DCD donors, high donor risk index).
  • Applying a practical viability assessment framework for livers on NMP, including hemodynamics, bile production, lactate trajectory, and histology when indicated.
  • Discussing the implications of NMP for allocation, system logistics, and future adoption trends in transplantation
Course summary
Available credit: 
  • 0.50 AMA PRA Category 1 Credit(s)™
  • 0.50 ANCC
  • 0.50 Attendance
  • 0.05 IACET CEU
Registration Opens: 
11/15/2025
Registration Expires: 
11/14/2027
Part of: 
Behind the Knife Podcast (ENDURING)
Rating: 
0
Virtual, NC
United States
  • Madeline Cloonan
  • Jacqueline Dauch
  • Shaheed Merani
  • Alan Langnas 

 

  • AMA PRA Category 1 Credit(s)
  • ANCC
  • Attendance
  • JA Credit - AH

Available Credit

  • 0.50 AMA PRA Category 1 Credit(s)™
  • 0.50 ANCC
  • 0.50 Attendance
  • 0.05 IACET CEU
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