In this course, we evaluate strategic IT investments in healthcare with the goal of increasing efficiency, reducing costs, and improving outcomes through the targeted application of health analytics. We will analyze and discuss case studies that illustrate the use of health analytics in support of patient safety, clinical efficacy, and fiscal responsibility. We will illustrate the data standards and modeling conventions used in medical informatics, and how they relate to health analytics. The course will be taught through didactic lectures, business-related cases, analysis of current information system challenges and opportunities for measurable return on investment in healthcare information technology. We will integrate current events throughout class discussion. Most classes will begin with discussion and analysis of a current healthcare challenge, and will conclude with additional insight on the application of strategies to address these challenges.