This course is designed for both healthcare and non-healthcare professionals who work with youth and young adults who would like a deeper and more practical understanding of the problem of tobacco use among young people, and opportunities to prevent and treat tobacco use and its sequelae. Grounded in a developmental framework, the course will explore the neurobiological and neurodevelopmental underpinnings of tobacco use and addiction among youth, the physiological and broader health impacts of use, the current prevalence of use and opportunities for community-based prevention, and essential clinical skills and resources involved in treating tobacco use disorders at the point of care, including behavioral and medication treatments. Learning Objectives: • Describe the scope of tobacco use among adolescents and young adults, including the varied types of use and key trends over time • Frame tobacco prevention and treatment within the neurodevelopmental context of adolescence • Identify opportunities for primary prevention of tobacco use among children and youth • Delineate practical strategies and evidence-based tools for screening for and assessing tobacco use among adolescents and young adults in busy clinical settings • List key medication and behavioral treatment options for youth using tobacco • Devise concrete approaches to addressing operational challenges in providing tobacco treatment to youth across a range of settings