How to Play Rheumatology Mechanism Madness

1)      Take a bracket (or download from email).

2)      Read the scouting reports for each team.  Additional information about some of the “underdogs” will be presented at grand rounds on 3/26, however attendance at that grand rounds is not required to participate.

3)      For each matchup, choose the team that you think represents the most important pathogenic mechanism for that region’s disease.  For example, in the RA region, decide if the shared epitope is more important than NFkB signaling in RA pathogenesis.  The winner of that matchup then plays FLS tech (fibroblast-like synoviocytes), etc.

4)      In the championship, choose the disease concept that you think is most important in the pathogenesis of disease for its original region.  For example, if you have protein modification from the RA region playing NETosis from the gout region in the championship, you would decide if protein modification in RA is more or less important than NETosis in gout.

5)      The winners of each matchup will be chosen by live voting at grand rounds on 3/26.

6)      Each “win” in the 1^st round = 1 point, 2^nd round = 2 points, 3^rd round = 4 points, and selecting the correct champion = 8 points.

7)      The overall scores will be tabulated after 3/26 and the winner will be announced via email and at a subsequent grand rounds.

How to Submit Your Bracket

1)      If you are NOT attending grand rounds on 3/26, please submit your bracket to David Leverenz by email by 8am on 3/26.  You can submit by:

a.       Email: [email protected]

b.      Text a picture of your bracket to David Leverenz at 817-319-3676

2)      If you ARE attending grand rounds on 3/26, you will have the opportunity to finalize your brackets and submit at that session.

3)      Make sure your name is on your bracket!