State of the Science: Clinical, Metabolic and Pathologic Effects of Multiple Concussions

Date/Time: On Demand, 8-30 September 2014

During the past few years, professional athletes and their families have become increasingly concerned about the long-term neurologic effects of repeated concussions. The premature deaths of several professional football players have drawn attention to the relationship of multiple concussions with neurocognitive disorders that occurred decades after these injuries, although similar changes in the brain were associated with boxing and first described in the 1920s.

The session will examine the findings of laboratory and clinical studies on the mechanisms responsible for brain injury following one or multiple concussions. The presentation will address a particular focus on a class of proteins called Tau protein and the association of some of the histologic features of multiple concussions with those of Alzheimer’s disease.

Target Audience: This program will be beneficial to mental health practitioners including psychologists, social workers, counselors, substance abuse professionals, case managers, clinicians and therapists. Any other mental health professionals are invited to attend.

1.25 contact hours. (Includes Social Work hours) NC AHEC is a 2014 NASW-NC approved provider of distance continuing education. This program has been approved for 1.25 contact hours. CEUs will be awarded to participants who attend 100% of this program. This program will provide 1.25 contact hours (category A) continuing education credit to NC Psychologists.


  • Describe the pathophysiology of concussion
  • Summarize the metabolic abnormalities caused by concussion, and the window of vulnerability of the brain to a second concussion
  • Identify the long-term changes in patterns of protein deposition possibly associated with multiple concussions
  • Articulate the possible association of multiple concussions and long-term cognitive deficits


Steven DeKosky, MD, FAAN, FACP, FANA
Visiting Professor, Department of Medical Ethics and Health Policy, Perelman School of Medicine at University of Pennsylvania, Philadelphia, Pa.
Professor of Neurology, Psychiatry and Behavioral Sciences, Director of the Alzheimer’s Disease Center, University of Virginia School of Medicine, Charlottesville, Va.

J. Clay Goodman, M.D., FAAN
Professor and Associate Dean, Departments of Pathology, Immunology and Neurology
Baylor College of Medicine
Houston, Tex.

David A. Hovda, Ph.D.
Director, University of California - Los Angeles Brain Injury Research Center
Professor of Neurosurgery and Molecular and Medical Pharmacology
David Geffen School of Medicine at UCLA
Los Angeles, Calif.


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  • Complete the course evaluation.
  • Attest to your hours of completion.
  • Download your certificate.


Continuing education credit is available from Duke Medicine for this On Demand session.

To receive credit, you must register no later than 6 p.m. (EDT) 26 September 2014 AND complete the course and evaluation no later than 11:59 p.m. (EDT) 26 September 2014.

Session registration opens 8 September 2014. The evaluation site opens at 8 a.m. (EDT) 8 September 2014 and closes at 11:59 p.m. (EDT) 26 September 2014.

DCoE's awarding of continuing education credit is limited in scope to health care providers who actively provide psychological health and traumatic brain injury care to U.S. active-duty service members, reservists, National Guardsmen, military veterans and/or their families.

To qualify for receipt of continuing education credit for this course, eligible participants must create a profile in the Duke Medicine Learning Management System and register for the event on, or before, the event registration deadline. Complete responses to all pre-registration questions are required to be eligible to receive credit for attending this event. For guidance on creating a user account and event registration in the Duke Medicine Learning Management System site, please visit

Course summary
Available credit: 
  • 1.25 AMA PRA Category 1 Credit(s)
  • 1.25 ANCC
  • 1.25 Attendance
  • 1.25 APA Credit
  • 0.13 CEU
  • 1.25 NASW credits
  • 1.25 NBCC
Registration Opens: 
Registration Expires: 

Available Credit

  • 1.25 AMA PRA Category 1 Credit(s)
  • 1.25 ANCC
  • 1.25 Attendance
  • 1.25 APA Credit
  • 0.13 CEU
  • 1.25 NASW credits
  • 1.25 NBCC
Please login or register to take this course.